Showing posts with label Human Genome Project. Show all posts
Showing posts with label Human Genome Project. Show all posts

Sunday, January 22, 2012

So we can read our genomes. Now what?

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So we can read our genomes. Now what?

The post-HGP (Human Genome Project) era has brought upon a new boom in genetic research due to the public availability of sequences at our fingertips. Despite many promising advances, many are impatient with the time that the HGP has taken or will take to bring upon potential clinical benefit for the health of the population. There are possible dangers associated with finding genes coding for diseases that are not yet curable, not providing any real benefit, but only anxiety in patients.

Based on this article and what we’ve learned in class and from our readings, what is your first impression of this article or sound byte? Do you think this will ever be a common medical practice? Now, think more critically, and discuss possible benefits and drawbacks of using this type of genome sequencing for clinical purposes if one day it does become affordable and readily available to the general population. (Think about privacy regulations, pharmacogenetics, discrimination, and genetic counseling to start.)

Click the link to access the NPR sound byte and associated article: http://www.npr.org/templates/story/story.php?storyId=126396839

Monday, January 24, 2011

What do we have to show for "it"?

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" Genomics is a way to do science, not medicine" -- Dr. Harold Varmus, National Cancer Institute Director

Given the amount of time and money spent on the Human Genome Project, New York Times writer, Nicholas Wade, suggests that the research has accomplished little in the direction of developing treatments for genetically-linked diseases. While the genome project has produced disappointing results for medicine but the research has contributed much to basic science. Knowing that genetic variants contribute a small fraction to the onset of a disease, where else should we be looking for other answers? What could and could not be learned from the HapMap?

Click here for the NYT news article: http://www.nytimes.com/2010/06/13/health/research/13genome.html

Monday, January 17, 2011

Magic DNA 8-Ball

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In 1946 the Magic 8-Ball was introduced - a toy to foretell events, to help make choices, and to seek advices. Today, many people still use the magical toy to help answer many life questions for fun or for serious guidance. Ask the Magic 8-ball a question and see the answer in the small window displaying one of the many dozen random messages such as "Yes",  "No",  "Certainly",  "Ask Again",  etc ... Proceed with life using your answer from the Magic 8-Ball.

The Figure below has an image of the double-helix DNA on the Magic 8-Ball window. 
What do you think is the meaning of this Magic DNA 8-Ball?